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Hubei Zhaoke Bio-Chemical Co., Ltd.

Yk11, Sarms, Gw-501516 manufacturer / supplier in China, offering ((17α , 20E) -17, 20-[ (1-methoxyethylidene) Bis- (oxy) ]-3-Oxo-19-Norpregna-4, 20-Diene-21-Carbo Sarms Yk11, Drostanolone Enanthate Steroid Raw Material Powder Male Enhancement, Fitness Anabolic Oxandrolon Steroid Anavar and so on.

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Supplier Homepage Product Sarms ((17α , 20E) -17, 20-[ (1-methoxyethylidene) Bis- (oxy) ]-3-Oxo-19-Norpregna-4, 20-Diene-21-Carbo Sarms Yk11

((17α , 20E) -17, 20-[ (1-methoxyethylidene) Bis- (oxy) ]-3-Oxo-19-Norpregna-4, 20-Diene-21-Carbo Sarms Yk11

FOB Price: US $1 / g
Min. Order: 50 g
Min. Order FOB Price
50 g US $1/ g
Get Latest Price
Port: Shanghai, China
Production Capacity: 100kg/Month
Payment Terms: T/T, Western Union, Money Gram
Basic Info
  • Model NO.: YK11
  • Customized: Customized
  • State: Powder
  • Classification: Fitness Sarms
  • Trademark: zhaoke
  • Specification: USP
  • Powder: Yes
  • Suitable for: Adult
  • Purity: >99%
  • Assay: 99%
  • Transport Package: Aluminum Foil Bag
  • Origin: China
Product Description
What is YK11?
(17α,20E)-17,20-[(1-methoxyethylidene)bis-(oxy)]-3-oxo-19-norpregna-4,20-diene-21-carboxylic acid methyl ester (YK11), which the myogenic differentiation of C2C12 myoblast cells is induced by the novel androgen receptor (AR) partial agonist. 
YK11 is a selective androgen receptor modulator (SARM), which activates AR without the N/C interaction. In this study, we further investigated the mechanism by which YK11 induces myogenic differentiation of C2C12 cells. The induction of key myogenic regulatory factors (MRFs), such as myogenic differentiation factor (MyoD), myogenic factor 5 (Myf5) and myogenin, was more significant in the presence of YK11 than in the presence of DHT. YK11 treatment of C2C12 cells, but not DHT, induced the expression of follistatin (Fst), and the YK11-mediated myogenic differentiation was reversed by anti-Fst antibody.
Myogenic differentiation is in reference to the products ability to block myostatin. Myostatin inhibition has been a really popular movement since the ban of most prohormones as it looks to be a relatively unexplored area for muscle growth and fat loss. There are currently a lot of claims about mystatin inhibition, but not so much factual data on these products. YK11 will have similar affects to DHT (possibly more potent) without the negatives of DHT. What this means is that the product will most likely be suppressive and require a post cycle, but not cycle support. It also won't have androgenic side affects like hair loss, acne, etc. The increase in follistatin caused by YK11 will act as an antagonist to mystatin (it will block myostatin) as well as the anabolic growth properties of YK11.
How it works?
Animal Research:
In direct comparison to to LGD-4033 as the reference for assay upon animal models of anabolism and androgenicity, YK-11 demonstrated higher efficacy withing anabolic parameters and lesser androgenicity at equivalent dosages.
It induces muscle cells to make more follistatin which is a strong myostatin inhibitor. Myostatin (also known as growth differentiation factor 8, is a myokine (protein) produced by muscle cells that acts on muscle cells to inhibit myogenesis. Myogenesis is muscle cell growth and differentiation. Research through the years show that when you block myostatin, it allows for significantly more muscle mass. So in research myostatin inhibitors are researched to find cures for muscle diseases.
We expect YK11 to be more potent than SARM LGD in terms of overall growth and feel. At this time, we expect this to be the strongest SARM on the market at a regular dosing. While suppression can occur, we expect this product to have low androgenic properties and can be used by both men and women. From our experience with SARMs, we find there are less losses of on-cycle results than pro-hormones, although typically not as potent. We do expect this product to have similar results as a moderately dosed Halodrol, without the alpha-male/androgenic feelings while on it.
Dosages and Suggestion
Recommended maximum dose YK11 is require dosages of 2.0-5.0mg b.i.d. in males and 0.5mg-2mg b.i.d. in females to achieve optimal effects in humans for the noted indications.


We are supplying:
NONameCAS NO
1MK2866841205-47-8
2MK-67715972-10-0
3LGD-40331165910-22-4
4GW1516317318-70-0
5Andarine(S4)401900-40-1
6SR90091379686-30-2
7RAD1401182367-47-0
8YK11431579-34-9
 
Peptides1 Vial
CJC 1295 WITHOUT DAC2MG
CJC1295 WITH DAC2MG
GHRP-2 5MG
GHRP-6 5MG
HMG75IU
HEXARELIN2MG
MELANOTAN I10MG
MELANOTAN II10MG
MGF2MG
MGF PEG2MG
EPTATON(EPITHALON)10MG
PT-14110MG
SELANK 2MG
SERMORELIN 5MG
Triptorelin2MG
TB-5002MG
ace 0311MG
H*CG5000IU
EP*O3000IU
GH blue/red/green/yellow tops10IU
BRAND GH Jin/Kig/Rip/Hyge10IU
IG**F-1 LR31MG
 
NameAbbr.
TestosteronT
Testosterone EnanthateTE
Testosterone CypionateTC
Testosterone IsocaproateTI
Testosterone DecanoateTD
Testosterone UndecanoateTU
Testosterone PropionateTP
Testosterone PhenylpropionateTPP
Testosterone AcetateTA
Sustanon250(Testosteron mixed)S250
  
BoldenonB
Boldenone acetateBA
Boldenone UndecylenateBU
Boldenone CypionateBC
  
NandrolonN
Nandrolon  DecanoatND
Nandrolone CypionateNC
Nandrolone UndecylateNU
Nandrolone PhenylpropionateNPP
  
Oxandrolon (Anavar)OA
Oxymetholon (Anad)Oxy
Stanozolo  (Winstrol)ST
Metandienon(Danabol)DB
Methenolone acetateMA
Methenolone enanthateME
Trenbolone acetateTRA
Trenbolone EnanthateTRE
Drostanolone EnanthateDE
Drostanolone PropionateDP
  
Tamoxifen Citrate (Nolvadex)Nolv
Clomiphene Citrate (Clomid)/
L-Triiodothyronine(T3)T3
Anastroz (Arimidex)Ana
  
Trilostane/
  
Exemest(Aromasin)/
  
Silde citrate Via
Tadalaf Tada

High purity
Fast and safe delivery
Please feel free to contact us and we will do our best to help you. Thank you.

((17α , 20E) -17, 20-[ (1-methoxyethylidene) Bis- (oxy) ]-3-Oxo-19-Norpregna-4, 20-Diene-21-Carbo Sarms Yk11

((17α , 20E) -17, 20-[ (1-methoxyethylidene) Bis- (oxy) ]-3-Oxo-19-Norpregna-4, 20-Diene-21-Carbo Sarms Yk11
((17α , 20E) -17, 20-[ (1-methoxyethylidene) Bis- (oxy) ]-3-Oxo-19-Norpregna-4, 20-Diene-21-Carbo Sarms Yk11

((17α , 20E) -17, 20-[ (1-methoxyethylidene) Bis- (oxy) ]-3-Oxo-19-Norpregna-4, 20-Diene-21-Carbo Sarms Yk11

Hubei Zhaoke Bio-Chemical Co., Ltd.
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